Benzonase Nuclease

Benzonase Nuclease, also known as unrestricted endonuclease and broad-spectrum nuclease, is a nuclease derived from SerratiaMarcescens and modified by genetic engineering. It can degrade all forms of DNA and RNA, including double-helical, single-stranded, double-stranded, linear, circular, natural and denatured nucleic acids, into 5' -monophosphate oligonucleotide fragment 3-5 bases long, and it is effective under a variety of operating conditions. It is widely used because it has no special requirement for nucleic acid base sequence and can be cut between any nucleotides in the chain.